Most skin lesions are benign; however, some concern has caused the patient to make an inquiry, and a correct diagnosis is important. The plethora of dermatologic conditions makes a correct diagnosis challenging. To combat this, the physician must approach the evaluation of the lesion in a systematic way. In addition to the physical characteristics of the lesion, the patient’s demographics, presence of associated symptoms, related systemic disorders, and location and growth patterns of the lesion all give clues to adequately diagnose and treat. The accurate diagnosis of any skin lesions can be made by histologic examination of a skin biopsy. It is important that common benign lesions are correctly identified so to distinguish those skin conditions that do need a biopsy and possible further treatment. Please inform your physician of any lesions you have so that Dr. Dubin can do the proper evaluation.