Bio Identical Hormone Replacement Therapy (BHRT) is the use of supplemental doses of hormones that have a chemical structure identical to the hormones the human body naturally produces. BHRT treats the symtoms of menopause perimenopause and postmenopause. Bioidentical hormones are applied via a cream, a suppository, taken orally or are injected.

After a patient is determined to be in hormonal decline, the physician will administer static dosing, which is when hormone levels are approximated and a patient is prescribed the same amount of estradiol every day of the month. On days 18 to 28 the doctor would prescribe a static dose of progesterone to imitate what the body made previously.